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MCN
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PostPosted: 03:08 - 29 Mar 2020    Post subject: Reply with quote

- wrote:
Looking at the US economy prior to China’s little “oops”, i’d Say he’s done an astounding job. Maybe too good a job for China.

He speaks his mind, unlike Obama, who recites pre prepared speeches.

If we’re honest about this, he’s a left wing hate figure, mainly because he scares them for doing a good job. If he was another Corbyn he’d be no threat to lefties.


He speaks his mind.

Is not a fantastic character trait if the person speaking is a Narcissistic Orange.
Enoch Powel spoke his mind and he was a dick.
Adolf Tiberius Hitler.
Slobodan Milosevic.
Didi Amin.
Pol Pot.
Jimmy Savile.

He has 'mutated' his stance on Corona Virus 2019 every time a different 'fake' news report surfaces.

He plainly does not understand any of the sophistications of biology or genetics so should not opine with his flawed unintuitive theory (hunches).

He's so empowered by his ego that he refuses to listen to reason.

He is not the person to be at the helm here.

Nothing he has enforced so far has been as a result of him reading the room.
It's reactionary and always a step too late.
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MCN
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PostPosted: 04:57 - 29 Mar 2020    Post subject: Reply with quote

Bad Medicine
https://www.bbc.com/future/article/20200323-coronavirus-will-hot-weather-kill-covid-19

A major contribution to 'seasonal' virus spread is due to cold weather. But with important caveats
People tend to keep windows and doors closed to conserve expensive heat energy and the air in buildings get re-circulated with any pathogen in the air flow.

Human activity in close and closed proximity to other infected/infective humans spread disease.
But there is no pertinent link to ambient temps causing flu-ish disease.

You can still get URTI in summer.
Quite common in dessert or tropical regions at 30° Centipede +. (Especially where air conditioning is used and poorly maintained.)

Some high end HVAC have super heaters built in to Kill pathogens in the serviced air before the air is cooled. Especially in large buildings where lots of dirty humans circulate.
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Kawasaki Jimbo
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PostPosted: 11:05 - 29 Mar 2020    Post subject: Reply with quote

- wrote:
What are the chances of that, eh? Wink

Take your pick, it's a popular genre.
https://www.thewrap.com/virus-outbreak-movies-coronavirus-hackers-seventh-seal-contagion/
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Hong Kong Phooey
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PostPosted: 11:23 - 29 Mar 2020    Post subject: Reply with quote

stinkwheel wrote:
mentalboy wrote:

So, asymptomatic cases.
If one catches the virus but remains asymptomatic does this mean that their body does not reject the infection, do they, therefore, not build up antibodies and thus become super spreaders?


Doesn't seem to be the case with this one (yet), although it can happen with other viruses. In fact, it can happen with other types of coronavirus.

Broadly speaking, for a carrier state to occurr with a viral infection, the disease needs to find part of the body where the immune system can't reach it. The classic example is the chickenpox virus which lodges in nerve fibres and can reappear at a later stage as shingles. HIV is another which hides within the immune cells themselves.

It's one reason why they were worried about finding this strain of coronavirus in faeces because some parts of the gut are quite well "hidden" from the immune system. Other types of coronavirus in other species can have quite a prolonged faecal shedding period. In fairness though, this isn't as big a problem in humans on the whole because we don't lick one anothers arses quite as much and many of us even wash our hands after going to the toilet.

I wouldn't have said that being asymptomatic means you didn't form an adequate immune response. It can mean your immune system was already on top of the job and stomped on it fast. Its certainly being recognised that if your immune system is already activated (by, say a normal cold), some non-specific mechanisms are already ramped up and ready to go and the specific mechanisms are already out there looking for something to attack.

We've seen this in my field recently where you vaccinate an animal for one viral disease and it gives a significant protective effect when they are challenged by a totally different virus which the vaccine shouldn't really work against.

Can also work against you with some viruses. Almost all of the symptoms are as a result of the immune system attacking the virus rather than the damage the virus does in itself. This was seen during the post WW1 influenza epidemic where it particularly killed the fittest people by causing something called a "cytokine storm" as part of the immune response. The young and elderly were less badly affected. Doesn't look lke that's happening here though.

Another feature of coronaviruses is they can undergo point mutations. We se this all the time in cats with a diease called Feline Infectious Peritonitis. Most cats contract a mild coronavirus of the gut at some point and show few, if any symptoms. In an unlucky few, it mutates to a highly virulent form that almost always kills them.

There is some talk of there being two sub-types of the COV19 virus. One causing milder symptoms than the other. It's not clear if there are two different strains going about or if some of them are undergoing a similar mutation to cause more virulent disease. If there are two strains, the next question is does having the mild form protect you from the severe form?

In any case, using a live RNA virus for a vaccine is not a fantastic idea due to that mutation risk. It's why an effective vaccine will take a while. They will almost certainly need to splice a bit of COV19 genetic material into a more stable virus that can't multiply in humans to make it trigger the immune system and show it parts of the COV19 bug. Then test it to make sure it doesn't cause any unexpected effects.

I do hope they are talking to veterinary virologists. they've been actively and intensely studying feline coronavirus for decades.


Rated as interesting as I never knew Teffers was a vet.

How long will lockdown continue before a higher proportion of people get edgy, and ignore advice due to 'taking care of my mental health innit'?

I foresee social stigma and threats of penalties working short term, on the whole,
but as there's no way currently to eradicate it from the face of the planet we can't be kept indoors forever.

Lack of random testing means we have no idea where we're at. In the Netherlands they're testing regular blood donations for presence of CV19 antibodies. This should at least indicate what proportion of the "healthy" populace have had exposure, meaning they'll be much more able to judge the start of their end game.

Similarly in Iceland, random testing has enabled them to manage their response much better than anywhere else, they're pretty much open for business. Yes, it's a much smaller and managed population but nonetheless the point remains.

Here were only testing sports people, actors, celebrities, ministers and royalty, or people who obviously have it, anyone in the NHS or people with mild symptoms aren't worthy.

I see an interesting summer ahead, plenty of people unfortunately dead, and selfish folk continuing to spread it at a rate higher than we're able to treat. All the while refining the model on best guesses, garbage in garbage out.
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stinkwheel
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PostPosted: 12:08 - 29 Mar 2020    Post subject: Reply with quote

Random testing isn't the way. Targetted testing based on epidemiological models is the way.

The more infectious the disease, the fewer need to be tested to glean useful statistical data.

The next question is what do you do with that information? Can peoople who have had it come out of isolation? Do they have to have papers to prove it? Where does that lead?

A rapid, reliable antigen test would be handy so people know if they have a cold or cov19
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Easy-X
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PostPosted: 12:10 - 29 Mar 2020    Post subject: Reply with quote

Worth pointing out that while the word "Coronavirus" might not have been in general parlance till last year medically it's been around for ages.

If one were writing about a SARS-like virus and you wanted an alternative name then it's just a few clicks through wikipedia.
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Pjay
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PostPosted: 12:45 - 29 Mar 2020    Post subject: Reply with quote

Isn't SARS also a Coronavirus?
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Hong Kong Phooey
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PostPosted: 12:53 - 29 Mar 2020    Post subject: Reply with quote

stinkwheel wrote:

The next question is what do you do with that information? Can peoople who have had it come out of isolation? Do they have to have papers to prove it? Where does that lead?


We need a tattoo or tag on the ear, or coloured paint on the flanks.
Once you're cleared you can play out.

In the UK, 11% of tests have confirmed positive cases of Covid-19 by March 27. As these tests were targeted & presumably not random, we're not sure how to extrapolate that result.

0.18% of the population who are hypochondriacs and/or rich & famous tested to date - and like an MOT it only means a pass/fail on the day of the test.

Where are we right now? Apparently as just announced, it'll be continuing for some time longer than anticipated.
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Hong Kong Phooey
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PostPosted: 12:55 - 29 Mar 2020    Post subject: Reply with quote

Pjay wrote:
Isn't SARS also a Coronavirus?


Yes. Not as infectious thankfully.
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Easy-X
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PostPosted: 15:45 - 29 Mar 2020    Post subject: Reply with quote

Hong Kong Phooey wrote:
We need a tattoo or tag on the ear, or coloured paint on the flanks...


Maybe a star sewn on your coat Shocked
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Nobby the Bastard
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PostPosted: 15:49 - 29 Mar 2020    Post subject: Reply with quote

Easy-X wrote:
Hong Kong Phooey wrote:
We need a tattoo or tag on the ear, or coloured paint on the flanks...


Maybe a star sewn on your coat Shocked


Now who's tormenting donk?
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Kawasaki Jimbo
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PostPosted: 17:56 - 29 Mar 2020    Post subject: Reply with quote

- wrote:
WTF are those massive lorries hurling into the air at night

Old news. They're putting on a show for the masses, that's all. Maybe if we did that it would make people take things more seriously? Nah, wouldn't work, most of us aren't that gullible.
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doggone
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PostPosted: 18:12 - 29 Mar 2020    Post subject: Reply with quote

They tend to do that disinfecting thing about once a month anyway it's for cockroaches and mosquitoes normally.
It seems like a collection gathered over some time, there isn't much to suggest it shows an ongoing massive problem, but you can bet the real figures are at least ten times official.

Our half hearted lockdown will make very little difference the only solution in the light of no vaccine for months is going to be let it rip and concentrate protection on the most vulnerable groups.
It's so infectious that nothing else will work.
Longer term the Countries that have more or less controlled it will struggle to keep that up indefinitely especially if the global economy is crashed by the useless restrictions too
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Polarbear
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PostPosted: 18:29 - 29 Mar 2020    Post subject: Reply with quote

Here's something a bit closer to home.

Sweden is the only country in Europe not doing a lock down.

Lockdown, what lockdown? Sweden's unusual response to coronavirus

https://www.bbc.co.uk/news/world-europe-52076293

What do you reckon? Sweden with millions dead or laughing at all the idiots in other countries? I really can't get my head on how they can be so different in their actions.
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Polarbear
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PostPosted: 18:54 - 29 Mar 2020    Post subject: Reply with quote

- wrote:
Polarbear wrote:
Here's something a bit closer to home.

Sweden is the only country in Europe not doing a lock down.

Lockdown, what lockdown? Sweden's unusual response to coronavirus

https://www.bbc.co.uk/news/world-europe-52076293

What do you reckon? Sweden with millions dead or laughing at all the idiots in other countries? I really can't get my head on how they can be so different in their actions.


To be fair, they're about 2 weeks behind us anyway. Expect lock down in 1 week as numbers take hold.


You would think, after seeing Italy and Spain, they would lock down now or do they have to let something happen before anyone takes any notice? Another conspiracy thought, perhaps they won't get people gaining immunity if they lock down too early?
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stinkwheel
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PostPosted: 19:27 - 29 Mar 2020    Post subject: Reply with quote

Mrs stinkwheels manager has asked staff by email how they would like to go about reducing the comapnies wages bill by 25%. Openly stated this is because central management are concerned they will be seeing an estimated 40% drop in turnover.

Would they preferr less pay, less hours, take an unpaid holiday or to keep pay the same but make up extra hours later in the year.

The (rather more tactfully worded) reply was along the lines of: None of the above. Suck it up. Everyones turnover will be down and the government is providing support to businesses so employees are not the ones taking the hit. I'm contracted to be paid a certain amouint for a certain number of hours and my household relies on this income. If you don't want to pay it, either make me redundant or furlough me.

According to companies house, The business in question has enough in the bank to cover all employee (and directors) pay for the next 12 months anyway and doubled both profit and turnover over the previous 12 months. This request for employees to accept reduced pay is purely to maintain the top-line, not to keep the business afloat. It stinks, I'm super pissed off they are even discussing it.
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bugeye_bob
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PostPosted: 20:20 - 29 Mar 2020    Post subject: Reply with quote

stinkwheel wrote:
bugeye_bob wrote:
Been sent this, make of it what you will,
Spreading the virus?


No. Just run of the mill stealing stuff from unlocked cars.


Why not lift the handle then. .
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Ste
Not Work Safe



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PostPosted: 20:26 - 29 Mar 2020    Post subject: Reply with quote

bugeye_bob wrote:
Been sent this, make of it what you will,
Spreading the virus?

Car hopping.
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