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orac
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PostPosted: 01:19 - 16 Feb 2016    Post subject: liver function tests Reply with quote

Just a third one, and for a fourth in for weeks time. I have a doctors appointment on Friday.

Each of the three tests have under back as abnormal, don't know how abnormal at this point. Do I start panicking that I have liver failure or cancer of some description. The tests not coming back normal car be a good thing
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CaNsA
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PostPosted: 01:24 - 16 Feb 2016    Post subject: Re: liver function tests Reply with quote

orac wrote:
Do I start panicking that I have liver failure or cancer of some description


Ask your doctor.
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The Wobbly Orange
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PostPosted: 02:13 - 16 Feb 2016    Post subject: Reply with quote

Chances are if you are not turning a funny colour or are being rushed anywhere it's not critical. Just avoid alcohol and try and live healthy til you know better one way or another.
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LustyLew
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PostPosted: 12:29 - 16 Feb 2016    Post subject: Reply with quote

Are you drinking heavily, or regularly?
Do you take a regular medication?
Do you take loads of protein shakes?
Do you take a lot of pain killers?

The liver can take quite a battering before serious damage occurs, but you do need to take care of it. I have to have 3 monthly tests due to meds that can do some serious damage if left unmonitored.

If you're genuinely worried, speak to your doctor about it at your next appointment.
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orac
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PostPosted: 17:14 - 16 Feb 2016    Post subject: Reply with quote

No
Just been put on thyroxin
No
Only when I get migraine, won't exceed max dose though. But can go on for a week or more a few time a year.

Doctors is bikes for Friday morning
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stinkwheel
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PostPosted: 17:51 - 16 Feb 2016    Post subject: Reply with quote

Another one in the back of the net for informed consent and physician/patient communication in the NHS. Rolling Eyes




Ask what (exactly) they were testing for and what the results you have mean. They should have explained the former when they took the test and thew latter when you got the result.

Incidentally, if you didn't starve yourself overnight and take a second test after eating, you haven't had a liver function test.
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.Chris.
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PostPosted: 18:16 - 16 Feb 2016    Post subject: Reply with quote

Which result (or results) are coming back as abnormal? How abnormal are they?
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orac
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PostPosted: 21:30 - 16 Feb 2016    Post subject: Reply with quote

stinkwheel wrote:
Another one in the back of the net for informed consent and physician/patient communication in the NHS. Rolling Eyes




Ask what (exactly) they were testing for and what the results you have mean. They should have explained the former when they took the test and thew latter when you got the result.

Incidentally, if you didn't starve yourself overnight and take a second test after eating, you haven't had a liver function test.


I work nights and don't fancy being starving while working. It's bad enough as it is. Hopefully Interrogate some more info out of the doc
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Ribenapigeon
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PostPosted: 09:07 - 18 Feb 2016    Post subject: Reply with quote

People do this all the time, go to the doc and forget to ask for specifics until after the consultation. What you need to do is write down your questions and concerns and take them to the appointment.
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GhostRider
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PostPosted: 19:55 - 18 Feb 2016    Post subject: Reply with quote

Well, the meaning behind the abnormal results will depend on what other symptoms you present with and what other tests are run alongside them.

Abnormal liver enzymes aren't necessarily an indication that there is a problem with the liver itself, but rather the livers reaction to other shit going on.

The fact that you say you have just been put on thyroxine suggests a suspicion of hypothyroidism. They haven't mentioned this at all at any stage?

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orac
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PostPosted: 01:31 - 22 Feb 2016    Post subject: Reply with quote

Enzymes are off by a small amount, should be max of 46 and mind is 51.

I was diagnosed with hypothyroidism before Xmas. Thyroid levels now look fine so things should start setting I hope. Currently taking 100micrograms of thyroxin a day

Never been tested for hep c as far as I know. Although the first blood test was a do set.

Just hate being stabbed with a needle in a monthly basis

I did learn rush that thyroxin is made from iodine, I am allergic to iodine bandages and fact but wonder if this needs to be taken into account. Time with tel I suppose
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CaNsA
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PostPosted: 02:27 - 22 Feb 2016    Post subject: Reply with quote

orac wrote:
I did learn rush that thyroxin is made from iodine, I am allergic to iodine bandages and fact but wonder if this needs to be taken into account. Time with tel I suppose


I hope you told your doctor, not just BCFers, about that allergy.
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orac
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PostPosted: 05:07 - 22 Feb 2016    Post subject: Reply with quote

It's in my notes, and I put it in my doctors registration form
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scorps
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PostPosted: 14:28 - 22 Feb 2016    Post subject: Reply with quote

dont worry too much, until they tell you they need to do a liver biopsy that is. Apparently 1 in a 1000 die from bleeding. I bled badly after my first one and who knew that the liver has a capsule full of nerve endings that stretch when its filling with blood and the pain makes you literally want to die to end it. but on a positive note, i was so anxious about getting another one, they sedated me so couldnt give a shit about a large needle being inserted between my ribs with a cutty thing while i was awake. Hope that makes you feel better Very Happy


PS hope its nowt serious.
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stinkwheel
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PostPosted: 20:26 - 22 Feb 2016    Post subject: Reply with quote

Elevated liver enzymes are not necessarily an indicator of liver damage. They can be but they aren't all specific. It's all in the interpretation.

So, In finding out what (exactly) they tested for and what the results you have mean. You've achieved neither.

You now know they tested at least one of the many biochemical indicators grouped as liver enzymes. You know one of them was slightly raised but not which one (some are more significant than others and which can indicate anything from damage to certain specific parts of the liver or just a general indication of cellular damage) and apparently STILL have no idea what this means.

This level of communication astounds me. You would get quicker service and a more thorough explanation if it was your cat that was ill. The only time I would report such a general result in liver enzymes to an owner is if they were all normal. Then I might say "There were no indications of ongoing liver damage.".

I'll take a wild guess that you have mildly elevated levels of alanine aminotransferase (ALT). This is released when you damage hepatocytes (the main liver cells responsible for food processing). It is fairly non-specific. Large increases indicate liver damage. A small increase in ALT can also be caused by muscle damage by bruising or heavy exercise. Several drugs can also cause it to be elevated.

An over high thyroid level can also cause elevations in ALT. I expect to see mildly elevated ALT in my animal patients with an overactive thyroid.

You can't be allergic to iodine. It isn't a large enough molecule to stimulate an antigenic response. You may be sensitive to something else within the iodine dressing you had. Most likely lanolin.
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orac
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PostPosted: 21:46 - 22 Feb 2016    Post subject: Reply with quote

I am fine with other lanolin products such as baby wipes

My thyroid is under active not over active
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stinkwheel
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PostPosted: 22:39 - 22 Feb 2016    Post subject: Reply with quote

orac wrote:
I am fine with other lanolin products such as baby wipes

My thyroid is under active not over active


Fine. But that notwithstanding, you're still not allergic to iodine. You're allergic to something else found in iodine-based dressings.

I presume you're on thyroxine supplimentation for your underactive thyroid? Getting the dose a bit on the high side would have the same biochemical effect as an overactive thyroid. It would increase your metabolic rate above normal which would potentially cause slight increases in your liver enzymes.

Just saying it's possible, not that's definately what it is. You doctor should know, just for some reason he/she appears not to have told you or you haven't heard/understood when they did (which is still their fault).
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I did the 2010 Round Britain Rally on my 350 Bullet. 89 landmarks, 3 months, 9,500 miles.
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orac
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PostPosted: 01:35 - 23 Feb 2016    Post subject: Reply with quote

They were high when I had the first test 3 months ago, which also the same test that showed the thyroid issue to start with.

Just had a 3 month test and thyroxin levels seem to be about right although enzymes are still alittle on the high side.

I did also react with the iodine in science when I was at school. That pretty much pure. It is very rare, I am also allergic to latex ad bananas. But not nuts which is also odd for someone with that allergy combination. There is evidenced that what you say could be taken as fact but also plenty to at that it's rare. I am nu going to do reading the medication if that's what you panicking about
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stinkwheel
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PostPosted: 09:42 - 23 Feb 2016    Post subject: Reply with quote

I'm not panicing at all. You asked about what your results mean, I'm just suggesting some things that might be responsible for your ill defined elevation in a liver enzymes since you clearly don't understand what you've been tested for and what the results mean. I'll stop now because it's a bit pointless.

Ask you doctor what (exactly) you have been tested for and what this result means. Keep asking until you get an answer you understand. Write your questions down before you go in next time.

I still don't believe there is such a thing as an allergy to iodine and scientifically am not aware of any mechanism in the body by which one could occurr. I've had a brief search of journals which corroborate what I stated earlier, your "iodine allergy" is almost certainly an allergy to some other componant of the dressings that were used.

There are a few unreferenced mentions of iodine allergy on some of the more hysterical allergy websites but nothing trustworthy.

Iodine itself is an irritant at higher concentrations. It is a caustic chemical that can cause burns and direct cellular damage in higher concentrations. That's why it's used as an antiseptic.

It's normally used medically (in dressings and as an antiseptic) at a level that kills bacterial cells but doesn't damage mammalian cells. It may be this happens to your cells at a lower concentration but the iodine content of thyroxine is several orders of magnitude smaller than you'd find in an iodine dressing.
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“Rule one: Always stick around for one more drink. That's when things happen. That's when you find out everything you want to know.
I did the 2010 Round Britain Rally on my 350 Bullet. 89 landmarks, 3 months, 9,500 miles.
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orac
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PostPosted: 06:00 - 24 Feb 2016    Post subject: Reply with quote

stinkwheel wrote:
iodine content of thyroxine is several orders of magnitude smaller than you'd find in an iodine dressing.


really, thought that the 100 micrograms pills I get to take daily were of a concentration so high it was going to brown, or maybe the horrible inflamed purple colour my skin goes when I come into contact with it. and if it applied to open wounds, it start getting really nasty. I am perfectly aware that the is iodine in food and drink, its something that our bodies need to get by. there are plenty of thing that we should not be allergic to, like surgical steel, I know 3 people who are allergic to it along with various other metals which include the very inert gold. just because you are not aware of it, does not mean that there is some odd ball out there that goes against the grain of general understanding. we normally call them freaks of nature.

honestly if you saw the my reaction to the stuff you would most likely change your tune. I am not willing to expose myself to it, same as goes for bananas and latex.
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scorps
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PostPosted: 09:31 - 24 Feb 2016    Post subject: Reply with quote

only issues I have is one form of antibiotic which makes me blister all over, adrenalin in local anesthetic has me spazzing like im having a fit and the common reaction to anything with nickel in it.
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